Erik Björn: Trace element speciation analysis-biogeochemical processes & metallomics of trace element compounds
The research concerns fundamental aspects, methodological developments and applications of speciation analysis of trace elements in environmental, biological and industrial samples.
The main objective is to provide fundamental understanding of chemical speciation, mechanisms and rate of reactions and interactions in the aquatic and terrestrial environments as well as in biological systems. The research is focused on formation of mobile and bioavailable forms of Hg in aquatic environments as well as fluxes and metabolism of Pt-containing chemotherapeutic substances in malignant cells.
Post-doctoral researchers: Lars Lambertsson, Gbotemi Adediram, Whei Zhu, Liem Nguyen Van
Ph.D. Students: Aleksandra Skrobonja
The overall objective with the research is to develop new powerful analytical techniques and methods for studies of trace element compounds’ biogeochemical processes in aquatic environments and metabolism in human cells.
We develop analytical methods and experimental strategies to determine; molecular structures of unknown trace metal compounds, concentrations of compounds and rate constants for their formation and degradation. We carry out experimental studies on both controlled model systems of varying complexity and complex natural systems at realistic conditions. The methods are based on state of the art techniques using stable enriched isotope tracers and chromatographic separations coupled to advanced elemental and molecular mass spectrometry techniques. Further we apply, in co-operation with our partners, in-house and synchrotron based spectroscopic measurement techniques as well as thermodynamic and kinetic modeling approaches to further assess chemical speciation and reactions. We use these measurement and modeling approaches in multi-disciplinary research projects where analytical chemistry is closely integrated with biogeochemistry, ecology, biochemistry and medicine sciences for advanced studies in the various experimental systems.