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Gerhard Gröbner: Protein-Lipid Assemblies Involved in Diseases

Virtually every biological process proceeds via membranes and their constituents. Therefore, my main research focus on the molecular aspects of the function and malfunction of membrane complexes with biological macromolecules.

Gerhard GröbnerIn particular, I apply biophysical techniques centered around biological solid state NMR to elucidate:
i) Membrane-mediated aggregation of amyloidogenic proteins involved in Alzheimer and ALS diseases;
ii) Structure/Function of integral membrane proteins;
iii) Antiapoptotic action of mitochondrial Bcl-2 Proteins.

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Koukalova, Alena
Amaro, Mariana
Aydogan, Gokcan; et al.

Lipid Driven Nanodomains in Giant Lipid Vesicles are Fluid and Disordered
Scientific Reports, 7

2017

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Dingeldein, Artur Peter Günther
Pokorna, Sarka
Lidman, Martin; et al.

Apoptotic Bax at Oxidatively Stressed Mitochondrial Membranes: Lipid Dynamics and Permeabilization
Biophysical Journal, 112(10): 2147-2158

2017

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Bugaytsova, Jeanna A.
Björnham, Oscar
Chernov, Yevgen A.; et al.

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence
Cell Host and Microbe, 21(3): 376-389

2017

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Lidman, Martin
Pokorná, Šárka
Dingeldein, Artur P. G.; et al.

The oxidized phospholipid PazePC promotes permeabilization of mitochondrial membranes by Bax
Biochimica et Biophysica Acta - Biomembranes, 1858(6): 1288-1297

2016

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Dingeldein, Artur P. G.
Lidman, Martin
Sparrman, Tobias; et al.

Dynamical and Structural Alterations withing Lipid-Protein Assemblies Control Apoptotic Pore Formation - A Solid State NMR Study
Biophysical Journal, 110(3): 59A-60A

2016

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Lidman, Martin
Dingeldein, Artur
Pokorná, Šárka; et al.

The Role of Lipids in Regulation of Programmed Cell Death
Biophysical Journal, 110(3): 473A-473A

2016

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Cheregi, Otilia
Miranda, Hélder
Gröbner, Gerhard; et al.

Inactivation of the Deg protease family in the cyanobacterium Synechocystis sp. PCC 6803 has impact on the outer cell layers
Journal of Photochemistry and Photobiology. B

2015

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Dingeldein, Artur P G
Lidman, Martin
Pokorna, Sarka; et al.

BCL-2 Family Proteins Effect on Mitochondrial-Mimicking Membrane Structure by Solid State NMR
Biophysical Journal, 108(2): 251A-252A

2015

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Vestergren, Johan
Ouattara, Korodjouma
Schleucher, Jurgen; et al.

Effect of Trees on Forms of Soil Phosphorus in an Agroforestry Parkland in Burkina Faso

2014

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Lidman, Martin
Wallgren, Marcus
Gröbner, Gerhard

Membranes and their lipids: a molecular insight into their organization and function

2014

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Sidansvarig: Gerhard Gröbner

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